Efficacy and tolerability of certolizumab pegol in Crohn's disease in clinical practice
نویسندگان
چکیده
منابع مشابه
Certolizumab pegol in the treatment of Crohn's disease.
INTRODUCTION The introduction of antibodies directed against tumour necrosis factor (anti-TNF) has dramatically changed the concept of treating patients with Crohn's disease (CD). Unfortunately, the long-term efficacy of anti-TNF agents may be hampered by immunogenicity. The availability of more anti-TNF agents in the therapeutic armamentarium would therefore be of great benefit in patients loo...
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Treatment with Anti-Tumor Necrosis Factor (anti-TNF) therapy has become a mainstay of therapy for patients with CD who are unresponsive to conventional medical management. Currently there are three anti-TNFα antibodies that have been approved by the US Food and Drug Administration for the treatment of CD, namely infliximab, adalimumab and certolizumab pegol (CZP). Several double blind placebo c...
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ژورنال
عنوان ژورنال: Terapevticheskii arkhiv
سال: 2018
ISSN: 2309-5342,0040-3660
DOI: 10.26442/terarkh201890674-80